Problems with BoNT use in ophthalmology arise on account of toxin diffusion or inadvertent placement to the adjacent muscles. Ptosis in the eyelid is the most common complication of BoNT treatment of strabismus and blepharospasms.23 Even though this result is nearly always short-term and self-resolving, apraclonidine 0.5% (Iopidine) or phenylepheri